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Furthermore, we demonstrated that RSL3 not only suppressed the spheroid formation, but also reduced the viability of PTC spheroids (Fig

The systemic administration of nanoparticles loaded with doxorubicin, furthermore, inhibited tumor-growth of SCC7 head and neck cancer xenograft models by over 70% compared to non-treated control mice and by over 40% in comparison with conventional free doxorubicin-treated mice without severe side effects

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